Human Membrane Protein Atlas Program
發布時間:2017-10-20         瀏覽人次:         發布人:Abmart Marketing


Revolutionary Products for Your Research:


2  Catalog Products: Membrane Protein Antibodies

2  Custom Antibody Services

2  Biomarkers and Novel Drug-Targets Discovery


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Core Technology: MabArrayTM

MabArrayTM is a high-throughput antibody library platform for profiling the specificity of antibodies and other molecules that target human membrane proteins.

Figure1: MabArrayTM technology platform


We developed revolutionary technology, MabArrayTM, a high-content arrayed monoclonal antibody library dramatically reduces the time and cost for antibody discovery, enabling on-demand generation of renewable protein binders at proteome-scale efficient target discovery in phenotypic screening, disease biomarkers and therapeutic targets.

The key feature of the MabArrayTM is that human membrane proteins are individually expressed and tested in their native state directly within human cells, thereby retaining their structural integrity and native post-translational modifications.


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Conclusion

The MabArrayTM represents a rapid, comprehensive, and highly sensitive platform for identifying the membrane protein targets of a wide variety of antibodies, protein ligands, and functional interactions. The platform has been validated for use in determining target specificity, deorphaning antibodies, and identifying cancer drug targets, Receptors/Ligands, thereby de-risking lead candidate selection, establishing new intellectual property and facilitating the discovery of new disease targets.


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